• 2. Introductory Chemistry

    Units: 4

    Lecture, two hours; discussion, two hours. Not open to students with credit for course 14A or 20A. Concept of submicroscopic world of chemistry, ranging from protons to proteins in subject matter. P/NP or letter grading.

  • 7. Nanoscience and Nanotechnology Laboratory

    Units: 2

    Seminar, discussion, and laboratory, 32 hours. Limited to high school students. Key concepts of nanoscience and nanotechnology, including various approaches to nanofabrication (bottom-up and top-down). Fabrication of nanostructures and devices, collection of scientific data using those devices, analysis of data, and presentations of student results. Offered in summer only. P/NP grading.

  • 14A. Atomic and Molecular Structure, Equilibria, Acids, and Bases

    Units: 4

    Lecture, three hours; discussion, one hour. Preparation: high school chemistry or equivalent background and three and one half years of high school mathematics. Enforced corequisite: Life Sciences 30A or Mathematics 3A or 31A or score of 35 or better on Mathematics Diagnostic Test. Not open to students with credit for course 20A. Introduction to physical and general chemistry principles; atomic structure based on quantum mechanics; atomic properties; trends in periodic table; chemical bonding (Lewis structures, VSEPR theory, hybridization, and molecular orbital theory); gaseous and aqueous equilibria; properties of inorganic and organic acids, bases, buffers; titrations. P/NP or letter grading.

  • 14B. Thermodynamics, Electrochemistry, Kinetics, and Organic Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisite: course 14A with grade of C- or better. Enforced requisite or corequisite: Life Sciences 30B or Mathematics 3B or 31B with grade of C- or better. Not open to students with credit for course 20A, 20B, or 30A. Phase changes; thermochemistry; first, second, and third laws of thermodynamics; free energy changes; electrochemistry and its role as energy source; chemical kinetics, including catalysis, reaction mechanisms, and enzymes; coordination compounds; general classes and naming of organic molecules; structure, conformations, and relative energies of organic molecules; application of thermodynamics and kinetics to organic and biochemical reactions; use of molecular modeling software to illustrate molecular structures and their relative energies. P/NP or letter grading.

  • 14BL. General and Organic Chemistry Laboratory I

    Units: 3

    Lecture, one hour; laboratory, three hours. Enforced requisite: course 14A with grade of C- or better. Enforced corequisite: course 14B. Not open to students with credit for course 20L. Introduction to volumetric, spectrophotometric, and potentiometric analysis. Use and preparation of buffers and pH meters. Synthesis and kinetics techniques using compounds of interest to students in life sciences. P/NP or letter grading.

  • 14C. Structure of Organic Molecules

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisite: course 14B with grade of C- or better. Not open to students with credit for course 30A. Continuing studies in structure of organic molecules, with emphasis on biological applications. Resonance, stereochemistry, conjugation, and aromaticity; spectroscopy (NMR, IR, and mass spectrometry); introduction to effects of structure on physical and chemical properties; survey of biomolecular structure. P/NP or letter grading.

  • 14CL. General and Organic Chemistry Laboratory II

    Units: 4

    Lecture, one hour; laboratory, six hours. Enforced requisites: courses 14B and 14BL, with grades of C- or better. Enforced corequisite: course 14C. Synthesis and analysis of compounds; purification by extraction, chromatography, recrystallization, and sublimation; characterization by mass spectroscopy, UV, NMR, and IR spectroscopy, optical activity, electrochemistry, pH titration. P/NP or letter grading.

  • 14D. Organic Reactions and Pharmaceuticals

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisite: course 14C with grade of C- or better. Organic reactions, nucleophilic and electrophilic substitutions and additions; electrophilic aromatic substitutions, carbonyl reactions, catalysis, molecular basis of drug action, and organic chemistry of pharmaceuticals. P/NP or letter grading.

  • 17. Chemical Principles

    Units: 4

    Lecture, three hours; discussion, one hour. Introduction to chemical principles: numbers, measurements, chemical calculations, gas laws, solutions, acids, bases, and salts, molecular structure, and nomenclature. Collaborative learning and problem solving; introduction to chemistry laboratory practice. P/NP or letter grading.

  • 19. Fiat Lux Freshman Seminars

    Units: 1

    Seminar, one hour. Discussion of and critical thinking about topics of current intellectual importance, taught by faculty members in their areas of expertise and illuminating many paths of discovery at UCLA. P/NP grading.

  • 20A. Chemical Structure

    Units: 4

    Lecture, three hours; discussion, one hour. Preparation: high school chemistry or equivalent background and three and one half years of high school mathematics. Recommended preparation: high school physics. Enforced corequisite: Mathematics 31A. First term of general chemistry. Survey of chemical processes, quantum chemistry, atomic and molecular structure and bonding, molecular spectroscopy. P/NP or letter grading.

  • 20AH. Chemical Structure (Honors)

    Units: 4

    Lecture, three hours; discussion, one hour. Preparation: high school chemistry or equivalent background, high school physics, and three and one half years of high school mathematics. Enforced corequisite: Mathematics 31A. Honors course parallel to course 20A. P/NP or letter grading.

  • 20B. Chemical Energetics and Change

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisites: course 20A or 20AH, and Mathematics 31A, with grades of C- or better. Enforced corequisite: Mathematics 31B. Second term of general chemistry. Intermolecular forces and organization, phase behavior, chemical thermodynamics, solutions, equilibria, reaction rates and laws. P/NP or letter grading.

  • 20BH. Chemical Energetics and Change (Honors)

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisites: course 20A and Mathematics 31A with grades of B+ or better or 20AH with grade of B or better. Enforced corequisite: Mathematics 31B. Honors course parallel to course 20B. Letter grading.

  • 20L. General Chemistry Laboratory

    Units: 3

    Lecture, one hour; laboratory, three hours. Enforced requisite: course 20A with grade of C- or better. Enforced corequisite: course 20B. Use of balance, volumetric techniques, volumetric and potentiometric analysis; Beer's law, applications for environmental analysis and materials science. P/NP or letter grading.

  • 30A. Organic Chemistry I: Structure and Reactivity

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisite: course 20B with grade of C- or better. First term of organic chemistry for Chemistry, Biochemistry, and engineering majors. Covalent bonding, shapes, stereochemistry, and acid/base properties of organic molecules. Properties, synthesis, and reactions of alkanes, cycloalkanes, alkenes, and alkynes. SN2, SN1, elimination, and radical reactions. P/NP or letter grading.

  • 30AH. Organic Chemistry I: Structure and Reactivity (Honors)

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisite: course 20B or 20BH, with grade of B+ or better. Honors course parallel to course 30A. P/NP or letter grading.

  • 30AL. General Chemistry Laboratory II

    Units: 4

    Lecture, one hour; laboratory, six hours. Enforced requisites: courses 20B (or 20BH), 20L, and 30A (or 30AH), with grades of C- or better. Qualitative and quantitative analysis of chemical reactions and compounds, kinetics, separations, and spectroscopy. P/NP or letter grading.

  • 30B. Organic Chemistry II: Reactivity, Synthesis, and Spectroscopy

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisite: course 30A or 30AH, with grade of C- or better. Second term of organic chemistry for Chemistry, Biochemistry, and engineering majors. Properties, synthesis, and reactions of alcohols, ethers, sulfur compounds, aldehydes, ketones, carboxylic acids, and carboxylic acid derivatives. Organometallic compounds. Organic spectroscopy, including mass spectrometry, infrared spectroscopy, and proton and carbon nuclear magnetic resonance spectroscopy. P/NP or letter grading.

  • 30BL. Organic Chemistry Laboratory I

    Units: 3

    Lecture, one hour; laboratory, four hours. Enforced requisites: courses 30A (or 30AH) and 30AL, with grades of C- or better. Enforced corequisite: course 30B. Basic experimental techniques in organic synthesis (distillation, extraction, crystallization, and performing reactions) and organic analytical chemistry (melting and boiling point, refractive index, chromatography, IR, NMR, GC). Single and multistep synthesis of known organic molecules on microscale level. P/NP or letter grading.

  • 30BL. Organic Chemistry Laboratory I

    Units: 3

    Lecture, one hour; laboratory, four hours. Requisites: courses 30A (or 30AH), 30AL and 30B, with grades of C- or better. Basic experimental techniques in organic synthesis (performing reactions, monitoring reactions, and conducting purifications) and spectroscopy (IR, NMR, mass spectrometry). Synthesis of known organic molecules on microscale level with focus on societal applications. P/NP or letter grading.

  • 30C. Organic Chemistry III: Reactivity, Synthesis, and Biomolecules

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisite: course 30B with grade of C- or better. Third term of organic chemistry for Chemistry, Biochemistry, and engineering majors. Chemistry of enolates, enamines, dicarbonyl compounds, and amines. Molecular orbital theory and conjugated pi systems; UV/vis spectroscopy. Aromaticity and reactions of aromatic molecules. Heterocycles, pericyclic reactions, carbohydrates, and lipids. P/NP or letter grading.

  • 30CL. Organic Chemistry Laboratory II

    Units: 4

    Lecture, two hours; laboratory, six hours. Enforced requisites: courses 30B and 30BL, with grades of C- or better. Enforced corequisite: course 30C. Modern techniques in synthetic organic and analytical organic chemistry. Semi-preparative scale, multistep synthesis of organic and organometallic molecules, including asymmetric catalysts. One- and two-dimensional multinuclear NMR techniques. Written reports and proposals. P/NP or letter grading.

  • 88A. Lower Division Seminar: Serendipity in Science

    Units: 2

    Seminar, two hours. Limited to 20 freshmen. Inquiry into unexpected discoveries in science that have had significant impact on society and analysis of circumstances that brought these about, beginning with discovery of helium in sun by Janssen in 1868 (using newly developed field of spectroscopy). Discovery of X rays by Röntgen in 1895 and of radioactivity by Becquerel in 1896. Other topics include discoveries important to medicine, such as penicillin by Fleming in 1928 and cis-platin by Rosenberg in 1969. P/NP or letter grading.

  • 89. Honors Seminars

    Units: 1

    Seminar, three hours. Limited to 20 students. Designed as adjunct to lower division lecture course. Exploration of topics in greater depth through supplemental readings, papers, or other activities and led by lecture course instructor. May be applied toward honors credit for eligible students. Honors content noted on transcript. P/NP or letter grading.

  • 89HC. Honors Contracts

    Units: 1

    Tutorial, three hours. Limited to students in College Honors Program. Designed as adjunct to lower division lecture course. Individual study with lecture course instructor to explore topics in greater depth through supplemental readings, papers, or other activities. May be repeated for maximum of 4 units. Individual honors contract required. Honors content noted on transcript. Letter grading.

  • 96. Special Courses in Chemistry

    Units: 1 to 4

    Tutorial, to be arranged. May be repeated for maximum of 8 units. P/NP or letter grading.

  • 98T. What Is Nanoscience?

    Units: 5

    Seminar, three hours. Enforced requisite: satisfaction of Entry-Level Writing requirement. Freshmen/sophomores preferred. Exploration of how nanoscience is used to solve real-world scientific and engineering problems. Hands-on experiments adapted from current research procedures and investigation of complex scientific questions related to those experiments. Letter grading.

  • 98XA. PEERS Collaborative Learning Workshops for Life Sciences Majors

    Units: 1

    Laboratory, three hours. Corequisite: associated undergraduate lecture course in chemistry and biochemistry for life sciences majors. Limited to Program for Excellence in Education and Research in Science (PEERS) students. Development of intuition and problem-solving skills in collaborative learning environment. May be repeated four times, but only 1 unit may be applied toward graduation. P/NP grading.

  • 98XB. PEERS Collaborative Learning Workshops for Physical Sciences and Engineering Majors

    Units: 1

    Laboratory, three hours. Corequisite: associated undergraduate lecture course in chemistry and biochemistry for physical sciences and engineering majors. Limited to Program for Excellence in Education and Research in Science (PEERS) students. Development of intuition and problem-solving skills in collaborative learning environment. May be repeated four times, but only 1 unit may be applied toward graduation. P/NP grading.

  • 99. Student Research Program

    Units: 1 to 2

    Tutorial (supervised research or other scholarly work), three hours per week per unit. Entry-level research for lower division students under guidance of faculty mentor. Students must be in good academic standing and enrolled in minimum of 12 units (excluding this course). Individual contract required; consult Undergraduate Research Center. May be repeated. P/NP grading.

  • C100. Genomics and Computational Biology

    Units: 5

    Lecture, four hours; discussion, one hour. Introduction for biochemistry students of technologies and experimental data of genomics, as well as computational tools for analyzing them. Biochemistry and molecular biology dissected life into its component parts, one gene at time, but lacked integrative mechanisms for putting this information back together to predict what happens in complete organism (e.g., over 80 percent of drug candidates fail in clinical trials). High-throughput technologies such as sequencing, microarrays, mass-spec, and robotics have given biologists incredible new capabilities to analyze complete genomes, expression patterns, functions, and interactions across whole organisms, populations, and species. Use and analysis of such datasets becomes essential daily activity for biomedical scientists. Core principles and methodologies for analyzing genomics data to answer biological and medical questions, with focus on concepts that guide data analysis rather than algorithm details. Concurrently scheduled with course C200. P/NP or letter grading.

  • 103. Environmental Chemistry

    Units: 4

    Lecture, four hours; discussion, one hour. Requisites: courses 30B, 30BL, 110A, 153A (or 153AH), 153L. Chemical aspects of air and water pollution, solid waste disposal, energy resources, and pesticide effects. Chemical reactions in environment and effect of chemical processes on environment. P/NP or letter grading.

  • C105. Introduction to Chemistry of Biology

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisite: course 153A with grade of C- or better. Introduction to chemical biology. Topics include computational chemical biology, utility of synthesis in biochemical research, peptidomimetics, designed reagents for cellular imaging, natural product biosynthesis, protein engineering and directed evolution, cell biology of metal ions, imaging metal ions in cells, metal-containing drugs. Concurrently scheduled with course CM205A. Letter grading.

  • C107. Organometallic Chemistry

    Units: 4

    Lecture/discussion, three hours. Enforced requisite or corequisite: course 172. Survey of synthesis, structure, and reactivity (emphasizing mechanistic approach) of compounds containing carbon bonded to elements selected from main group metals, metalloids, and transition metals, including olefin complexes and metal carbonyls; applications in catalysis and organic synthesis. Concurrently scheduled with course C207. P/NP or letter grading.

  • C108. Mass Spectrometry for Chemists and Biochemists

    Units: 2

    Lecture, one hour; laboratory, four hours. Requisite: course 153A. Introduction to principles and practice of organic and inorganic mass spectrometry. Topics include EI, CI, ICPMS, GC/MS, LC/MS, ESI, MALDI, MS/MS protein identification, and proteomics. Concurrently scheduled with course C208. P/NP or letter grading.

  • 110A. Physical Chemistry: Chemical Thermodynamics

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Requisites: course 20B, Mathematics 32A or 3C (for life sciences majors), Physics 1A, 1B, and 1C (may be taken concurrently), or 1AH, 1BH, and 1CH (may be taken concurrently), or 6A, 6B, and 6C (may be taken concurrently). Fundamentals of thermodynamics, chemical and phase equilibria, thermodynamics of solutions, electrochemistry. P/NP or letter grading.

  • 110B. Physical Chemistry: Introduction to Statistical Mechanics and Kinetics

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Requisites: courses 110A, 113A, Mathematics 32B. Kinetic theory of gases, principles of statistical mechanics, statistical thermodynamics, equilibrium structure and free energy, relaxation and transport phenomena, macroscopic chemical kinetics, molecular-level reaction dynamics. P/NP or letter grading.

  • 113A. Physical Chemistry: Introduction to Quantum Mechanics

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Requisites: course 20B, Mathematics 32A, 32B, 33A, Physics 1A, 1B, and 1C, or 1AH, 1BH, and 1CH, or 6A, 6B, and 6C, with grades of C- or better. Departure from classical mechanics: Schrödinger versus Newton equations; model systems: particle-in-box, harmonic oscillator, rigid rotor, and hydrogen atom; approximation methods: perturbation and variational methods; many-electron atoms, spin, and Pauli principle, chemical bonding. P/NP or letter grading.

  • 113A. Physical Chemistry: Introduction to Quantum Mechanics

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Requisites: course 20B, Mathematics 32A, 32B, 33B, Physics 1A, 1B, and 1C, or 1AH, 1BH, and 1CH, or 6A, 6B, and 6C, with grades of C- or better. Departure from classical mechanics: Schrödinger versus Newton equations; model systems: particle-in-box, harmonic oscillator, rigid rotor, and hydrogen atom; approximation methods: perturbation and variational methods; many-electron atoms, spin, and Pauli principle, chemical bonding. P/NP or letter grading.

  • C113B. Physical Chemistry: Introduction to Molecular Spectroscopy

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Requisite: course 113A. Interaction of radiation with matter, microwave spectroscopy, infrared and Raman spectroscopy, vibrations in polyatomic molecules, electronic spectroscopy, magnetic resonance spectroscopy. Concurrently scheduled with course C213B. P/NP or letter grading.

  • 114. Physical Chemistry Laboratory

    Units: 5

    Lecture, two hours; laboratory, eight hours. Enforced requisites: courses 30AL, 110A, and 113A, with grades of C- or better. Enforced corequisite: course 110B or C113B. Lectures include techniques of physical measurement, error analysis and statistics, special topics. Laboratory includes spectroscopy, thermodynamic measurements, and chemical dynamics. P/NP or letter grading.

  • 114H. Physical Chemistry Laboratory (Honors)

    Units: 5

    Lecture, two hours; laboratory, eight hours. Enforced requisites: courses 30AL, 110A, and 113A, with grades of B or better. Enforced corequisite: course 110B or C113B. Lectures include techniques of physical measurement, error analysis and statistics, special topics. Laboratory includes topics in physical chemistry to be selected in consultation with instructor. P/NP or letter grading.

  • C115A. Quantum Chemistry

    Units: 4

    Lecture, four hours; discussion, one hour. Requisites: course 113A, Mathematics 31A, 31B, 32A, 32B, 33A, with grades of C- or better. Recommended: knowledge of differential equations equivalent to Mathematics 134 or 135 or Physics 131 and of analytic mechanics equivalent to Physics 105A. Course C115A or Physics 115B with grade of C- or better is requisite to C115B. Students entering course C115A are normally expected to take course C115B in following term. Designed for chemistry students with serious interest in quantum chemistry. Postulates and systematic development of nonrelativistic quantum mechanics; expansion theorems; wells; oscillators; angular momentum; hydrogen atom; matrix techniques; approximation methods; time dependent problems; atoms; spectroscopy; magnetic resonance; chemical bonding. May be concurrently scheduled with course C215A. P/NP or letter grading.

  • C115B. Quantum Chemistry

    Units: 4

    Lecture, four hours; discussion, one hour. Requisites: course 113A, C115A or Physics 115B, Mathematics 31A, 31B, 32A, 32B, 33A, with grades of C- or better. Recommended: knowledge of differential equations equivalent to Mathematics 134 or 135 or Physics 131 and of analytic mechanics equivalent to Physics 105A. Students entering course C115A are normally expected to take course C115B in following term. Designed for chemistry students with serious interest in quantum chemistry. Postulates and systematic development of nonrelativistic quantum mechanics; expansion theorems; wells; oscillators; angular momentum; hydrogen atom; matrix techniques; approximation methods; time dependent problems; atoms; spectroscopy; magnetic resonance; chemical bonding. May be concurrently scheduled with course C215B. P/NP or letter grading.

  • C115C. Advanced Quantum Chemistry: Applications

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 113A, C115B. Topics in quantum chemistry selected from molecular structure, collision processes, theory of solids, symmetry and its applications, and theory of electromagnetic radiation. Concurrently scheduled with course C215C. P/NP or letter grading.

  • M117. Structure, Patterns, and Polyhedra

    Units: 5

    (Same as Honors Collegium M180.) Lecture, four hours; laboratory, two hours. Exploration of structures and their geometric underpinnings, with examples and applications from architecture (space frames, domes), biology (enzyme complexes, viruses), chemistry (symmetry, molecular cages), design (tiling), engineering (space filling), and physics (crystal structures) to effect working knowledge of symmetry, two-dimensional patterns, and three-dimensional solids. P/NP or letter grading.

  • 118. Colloidal Dynamics Laboratory

    Units: 4

    Lecture, two hours; laboratory, eight hours. Requisites: courses 110A and 110B, with grades of B or better, or equivalent statistical mechanics courses from engineering, mathematics, or physics. One aspect of dispersions of microscale particles in viscous liquids is that such dispersions can be used as visual model systems for studying phases that chemistry undergraduate students typically learn about for nanoscale and molecular systems, yet they do not see. Temperature continuously excites molecules and causes rearrangements, giving dynamic views of macromolecules and particles in many fields, including cell and molecular biology, chemical engineering, chemistry, materials science, and physics. Letter grading.

  • M120. Soft Matter Laboratory

    Units: 4

    (Same as Physics M180G.) Laboratory, four hours. P/NP or letter grading.

  • 121. Special Topics in Physical Chemistry

    Units: 4

    Lecture, four hours. Requisite: course 110B. Recommended: course 113A. Topics of considerable research interest presented at level suitable for students who have completed junior-year courses in physical chemistry. P/NP or letter grading.

  • C122. Mathematical Methods for Chemistry

    Units: 4

    Lecture, four hours. Enforced requisites: Mathematics 31A, 31B, 32A, 32B. Review of basic mathematics necessary to study physical chemistry at graduate level, with focus on review of vectors, linear algebra, elementary complex analysis, and solution of ordinary and partial differential equations. Development of problem-solving skills through homework based on these mathematical techniques, with examples from physical chemistry. Concurrently scheduled with course C222. P/NP or letter grading.

  • C123A. Classical and Statistical Thermodynamics

    Units: 4

    Lecture, four hours; discussion, one hour. Requisite: course 110B or 156. Recommended: course 113A. Rigorous presentation of fundamentals of classical thermodynamics. Principles of statistical thermodynamics: probability, ensembles, partition functions, independent molecules, and perfect gas. Applications of classical and statistical thermodynamics selected from diatomic and polyatomic gases, solid and fluid states, phase equilibria, electric and magnetic effects, ortho-para hydrogen, chemical equilibria, reaction rates, imperfect gas, nonelectrolyte and electrolyte solutions, surface phenomena, high polymers, gravitation. May be concurrently scheduled with course C223A. P/NP or letter grading.

  • C123B. Classical and Statistical Thermodynamics

    Units: 4

    Lecture, four hours; discussion, one hour. Requisite: course 110B or 156. Recommended: course 113A. Rigorous presentation of fundamentals of classical thermodynamics. Principles of statistical thermodynamics: probability, ensembles, partition functions, independent molecules, and perfect gas. Applications of classical and statistical thermodynamics selected from diatomic and polyatomic gases, solid and fluid states, phase equilibria, electric and magnetic effects, ortho-para hydrogen, chemical equilibria, reaction rates, imperfect gas, nonelectrolyte and electrolyte solutions, surface phenomena, high polymers, gravitation. May be concurrently scheduled with course C223B. P/NP or letter grading.

  • 125. Computers in Chemistry

    Units: 4

    Lecture, three hours; computer laboratory, one hour. Requisites: courses 110A and 113A, with grades of C- or better. Discussion of data acquisition and instrument control, scientific programming and data analysis, structural databases and molecular modeling methods. Hands-on computer laboratory experience with wide range of open source and commercial scientific software. P/NP or letter grading.

  • C126A. Computational Methods for Chemists

    Units: 4

    Lecture, four hours; laboratory, four hours. Preparation: programming experience in either BASIC, Fortran, C, C++, Java, or Pascal. Requisites: courses 110A, 113A, Mathematics 33A. Theoretical, numerical, and programming tools for constructing new chemical applications, including simple force fields and resulting statistical mechanics for simple molecules, simple ab-initio methods for organic molecules and nanotubes, and classical dynamics and spectroscopy. Concurrently scheduled with course C226A. P/NP or letter grading.

  • C126A. Computational Methods for Chemists

    Units: 4

    Lecture, four hours; laboratory, four hours. Preparation: programming experience in either BASIC, Fortran, C, C++, Java, or Pascal. Requisites: courses 110A, 113A, Mathematics 33B. Theoretical, numerical, and programming tools for constructing new chemical applications, including simple force fields and resulting statistical mechanics for simple molecules, simple ab-initio methods for organic molecules and nanotubes, and classical dynamics and spectroscopy. Concurrently scheduled with course C226A. P/NP or letter grading.

  • CM127. Synthetic Biology for Biofuels

    Units: 4

    (Same as Chemical Engineering CM127.) Lecture, four hours; discussion, one hour. Requisites: course 153A, Life Sciences 3, 23L. Engineering microorganisms for complex phenotype is common goal of metabolic engineering and synthetic biology. Production of advanced biofuels involves designing and constructing novel metabolic networks in cells. Such efforts require profound understanding of biochemistry, protein structure, and biological regulations and are aided by tools in bioinformatics, systems biology, and molecular biology. Fundamentals of metabolic biochemistry, protein structure and function, and bioinformatics. Use of systems modeling for metabolic networks to design microorganisms for energy applications. Concurrently scheduled with course CM227. Letter grading.

  • 136. Organic Structural Methods

    Units: 5

    Lecture, two hours; laboratory, eight hours. Requisites: courses 30C and 30CL, with grades of C- or better. Laboratory course in organic structure determination by chemical and spectroscopic methods; microtechniques. P/NP or letter grading.

  • C140. Bionanotechnology

    Units: 4

    Lecture, three hours. Requisites: courses 30C, 110A. Basic physical, chemical, and biological principles in bionanotechnology; materials and strategies for top-down and bottom-up fabrication of ordered biologically derived molecules, characterization and detection techniques, and biomimetic materials and applications at nanoscale. Concurrently scheduled with course C240. P/NP or letter grading.

  • C143A. Structure and Mechanism in Organic Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 30C and 30CL (may be taken concurrently), 110B, and 113A, with grades of C- or better. Mechanisms of organic reactions. Acidity and acid catalysis; linear free energy relationships; isotope effects. Molecular orbital theory; photochemistry; pericyclic reactions. May be concurrently scheduled with course C243A. P/NP or letter grading.

  • C143B. Mechanism and Structure in Organic Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisite: course C143A with grade of C- or better. Mechanisms of organic reactions; structure and detection of reactive intermediates. May be concurrently scheduled with course C243B. P/NP or letter grading.

  • 144. Practical and Theoretical Introductory Organic Synthesis

    Units: 5

    Lecture, two hours; laboratory, eight hours. Enforced requisites: courses 30C and 30CL, with grades of C- or better. Lectures on modern synthetic reactions and processes, with emphasis on stereospecific methods for carbon-carbon bond formation. Laboratory methods of synthetic organic chemistry, including reaction techniques, synthesis of natural products, and molecules of theoretical interest. P/NP or letter grading.

  • C145. Theoretical and Computational Organic Chemistry

    Units: 4

    Lecture, two hours; discussion, one hour; computer laboratory, one hour. Requisites: courses 30C, 113A. Applications of quantum mechanical concepts and methods to understand and predict organic structures and reactivities. Computational modeling methods, including laboratory experience with force-field and quantum mechanical computer calculations. Concurrently scheduled with course C245. P/NP or letter grading.

  • 147. Careers in Chemistry and Biochemistry

    Units: 2

    Seminar, two hours. Limited to juniors/seniors. Exploration of employment and career opportunities available to students. Different speakers give short presentations to describe their career paths in areas such as industry, government, research and development, education, law, and healthcare, explain how their education in chemistry and biochemistry helped them become successful, and what actual chemistry was used in their particular professions. Students learn and understand real-life applications of chemical concepts found in their coursework. P/NP grading.

  • C150. Research Integrity in Cellular Biology, Molecular Biology, and Biochemistry Research

    Units: 2 or 4

    Lecture, two hours; discussion, two hours. Data analysis and management, statistical methods, use of antibody and kit reagents, figure preparation, authorship, mentoring, human subjects protection, animal subject protection, and conflict of interest. May be repeated for credit. P/NP or letter grading.

  • 153A. Biochemistry: Introduction to Structure, Enzymes, and Metabolism

    Units: 4

    Lecture, four hours; discussion, one hour. Requisite: course 14D or 30B, with grade of C- or better. Recommended: Life Sciences 2, 3, 23L. Structure of proteins, carbohydrates, and lipids; enzyme catalysis and principles of metabolism, including glycolysis, citric acid cycle, and oxidative phosphorylation. P/NP or letter grading.

  • 153AH. Biochemistry: Introduction to Structure, Enzymes, and Metabolism (Honors)

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Requisite: course 14D or 30B, with grade of C- or better. Recommended: Life Sciences 2, 3, 23L. Honors course parallel to course 153A. P/NP or letter grading.

  • 153B. Biochemistry: DNA, RNA, and Protein Synthesis

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Enforced requisites: course 153A or 153AH, Life Sciences 2, 3, 23L. Nucleotide metabolism; DNA replication; DNA repair; transcription machinery; regulation of transcription; RNA structure and processing; protein synthesis and processing. P/NP or letter grading.

  • 153BH. Biochemistry: DNA, RNA, and Protein Sythesis (Honors)

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Enforced requisites: course 153A or 153AH, Life Sciences 2, 3, 23L. Honors course parallel to course 153B. P/NP or letter grading.

  • 153C. Biochemistry: Biosynthetic and Energy Metabolism and Its Regulation

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Requisite: course 153A or 153AH. Metabolism of carbohydrates, fatty acids, amino acids, and lipids; photosynthetic metabolism and assimilation of inorganic nutrients; regulation of these processes. P/NP or letter grading.

  • 153CH. Biochemistry: Biosynthetic and Energy Metabolism and Its Regulation (Honors)

    Units: 4

    Lecture, three hours; discussion, two hours. Requisite: course 153A or 153AH. Honors course parallel to course 153C. P/NP or letter grading.

  • 153D. Introduction to Protein Structural Biology

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisites: course 153A, Life Sciences 3. Proteins are diverse set of macromolecules that perform critical functions within cells, ranging from enzymes that catalyze metabolic reactions to proteins that enable pathogens to cause disease. Introduction to field of protein structural biology, that seeks to understand molecular basis of protein function through visualizing atomic structures and by investigating how alterations in protein structure affects function. Students gain fundamental understanding of protein structure and its relationship to function and learn how experimental and computational methods are used to determine three-dimensional structures of proteins. Hands-on training in computer graphics programs and online tools used to visualize and analyze protein structures. Letter gradin

  • 153L. Biochemical Methods I

    Units: 4

    Lecture, two hours; laboratory, four hours. Enforced requisites: courses 14BL and Life Sciences 23L, or 20L and 30AL, and 153A or 153AH (may be taken concurrently), with grades of C- or better. Integrated term-long project involving biofuel production in bacteria. Purification of key enzyme for alcohol production from bacteria via affinity chromatography. Assessment of protein amount, purity, and activity of enzyme. Techniques include protein determination by Bradford assay, polyacrylamide gel electrophoresis, immunoblotting, and enzyme activity assays to determine enzyme activity (Km, Vmax, inhibitor studies). P/NP or letter grading.

  • 154. Biochemical Methods II

    Units: 5

    Lecture, two hours; laboratory, eight hours. Enforced requisites: courses 153A or 153AH, 153B or 153BH, and 153L, with grades of C- or better. Recommended: course 156. Two to three major laboratory projects using biochemical laboratory techniques to investigate contemporary problems in biochemistry. Topics include transcription activation, molecular basis of DNA-protein interactions, biochemical basis of platelet activation, and initiation of blood clotting cascade. Experiments entail characterizing function of proteins, nucleic acids, and lipids involved in these processes. P/NP or letter grading.

  • C155. Mitochondria in Medicine, Biology, and Chemistry

    Units: 1

    Seminar, two hours every other week. Open to undergraduate and graduate science majors considering or currently conducting research in areas related to mitochondria. Large number of physiological and pathophysiological processes involve mitochondrial function and dysfunction. Focus on understanding how mitochondria metabolism, form, and function impact health and disease. Physiology and cell biology of healthy and dysfunctional mitochondria critically assessed at subcellular, cellular, tissue, and organismal levels. Topics include in-depth analyses of literature and critical evaluation of experimental design and methods of current research. Concurrently scheduled with course CM255. P/NP grading.

  • 156. Physical Biochemistry

    Units: 4

    Lecture, four hours; discussion, one hour. Requisites: courses 110A, 153A. Biochemical kinetics; solution thermodynamics of biochemical systems; multiple equilibria; hydrodynamics; energy levels, spectroscopy, and bonding; topics from structural, statistical, and electrochemical methods of biochemistry. P/NP or letter grading.

  • C159. Mechanisms of Gene Regulation

    Units: 4

    (Formerly numbered C159A.) Lecture, four hours. Requisite: course 153B. Mechanisms that control transcription in bacteria. Repression and activation at promoters. Sigma factors and polymerase binding proteins. Signal transduction pathways in transcription. Control of termination. Concurrently scheduled with course CM259. P/NP or letter grading.

  • C159A. Mechanisms in Regulation of Transcription I

    Units: 2

    First five weeks. Lecture, four hours. Requisite: course 153B. Mechanisms that control transcription in bacteria. Repression and activation at promoters. Sigma factors and polymerase binding proteins. Signal transduction pathways in transcription. Control of termination. Concurrently scheduled with course C259A. P/NP or letter grading.

  • CM160A. Introduction to Bioinformatics

    Units: 4

    (Same as Computer Science CM121.) Lecture, four hours; discussion, two hours. Enforced requisites: Computer Science 32 or Program in Computing 10C with grade of C- or better, and one course from Biostatistics 100A, 110A, Civil Engineering 110, Electrical Engineering 131A, Mathematics 170A, or Statistics 100A. Prior knowledge of biology not required. Designed for engineering students as well as students from biological sciences and medical school. Introduction to bioinformatics and methodologies, with emphasis on concepts and inventing new computational and statistical techniques to analyze biological data. Focus on sequence analysis and alignment algorithms. Concurrently scheduled with course CM260A. P/NP or letter grading.

  • CM160B. Algorithms in Bioinformatics and Systems Biology

    Units: 4

    (Same as Computer Science CM122.) Lecture, four hours; discussion, two hours. Enforced requisites: Computer Science 32 or Program in Computing 10C with grade of C- or better, and one course from Biostatistics 100A, 110A, Civil Engineering 110, Electrical Engineering 131A, Mathematics 170A, or Statistics 100A. Course CM160A is not requisite to CM160B. Designed for engineering students as well as students from biological sciences and medical school. Development and application of computational approaches to biological questions, with focus on formulating interdisciplinary problems as computational problems and then solving these problems using algorithmic techniques. Computational techniques include those from statistics and computer science. Concurrently scheduled with course CM260B. Letter grading.

  • C161A. Plant Biochemistry

    Units: 4

    Lecture, three hours; discussion, two hours. Requisite: course 153C. Introduction to distinctive features of plant biochemistry. Topics include photosynthesis, nitrogen metabolism, plant cell wall metabolism, and secondary metabolism in relation to stress. Concurrently scheduled with course C261A. P/NP or letter grading.

  • C163. Membrane Protein Structure and Function

    Units: 4

    Lecture, four hours. Enforced requisite: course 156. Detailed examination of how various membrane proteins work. Topics include lipid bilayer properties and how they affect membrane protein function and biology; membrane protein biogenesis; principles of transport across membranes; how channels, transporters, and receptors work at atomic level. Emphasis on reading and analyzing original research papers. Concurrently scheduled with course C263. P/NP or letter grading.

  • C164. Free Radicals in Biology and Medicine

    Units: 2 to 4

    Lecture, three hours. Enforced requisites: courses 153A and either 153B or 153C, with grades of C- or better. Biochemcial reactivity of dioxygen, its role in mitochondrial metabolism, neurodegenerative diseases, apoptosis, and aging. Discussion of radical reactions, how they are harnessed to achieve enzyme catalysis, and how free radicals contribute to or regulate essential biological processes. These same reactions "run amok" under certain types of stress and can contribute to wide variety of diseases, including neurodegenerative diseases (e.g., Huntington's, Parkinson's, and Alzheimer's diseases), mitochondrial diseases, atherosclerosis, and aging. Concurrently scheduled with course C264. P/NP or letter grading.

  • C165. Metabolic Control by Protein Modification

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 153A, 153B, 153C. Biochemical basis of controlling metabolic pathways by posttranslational modification of proteins, including phosphorylation and methylation reactions. Concurrently scheduled with course C265. Letter grading.

  • 166. RNA Structure, Recognition, and Function

    Units: 4

    Lecture, three hours; discussion, one hour. Enforced requisites: courses 153A, 153B, Life Sciences 3, 23L. Recent years have seen explosion in biochemical characterization of diverse structures and functions of RNA molecules in metabolism of living systems. RNA has been shown to act both as catalyst in living systems and as potent modulator of gene expression control at every level of gene expression pathways (transcription, RNA processing, translation, degradation). RNA molecules now being used as therapeutic agents in gene therapy approaches. Coverage of these various aspects and in-depth analysis of RNA structure and function, using primary research literature and analysis of molecular structures of RNA and RNA-protein complexes. Letter grading.

  • CM170. Biochemistry and Molecular Biology of Photosynthetic Apparatus

    Units: 2 to 4

    (Same as Molecular, Cell, and Developmental Biology M170.) Lecture, two to three hours; discussion, zero to two hours. Requisites: courses 153A and 153B, or Life Sciences 3 and 23L, and course 153L. Recommended: courses 153C, 154, Life Sciences 4. Light harvesting, photochemistry, electron transfer, carbon fixation, carbohydrate metabolism, pigment synthesis in chloroplasts and bacteria. Assembly of photosynthetic membranes and regulation of genes encoding those components. Emphasis on understanding of experimental approaches. Concurrently scheduled with course C270. P/NP or letter grading.

  • 171. Intermediate Inorganic Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisite: course 30B with grade of C- or better. Chemical bonding; structure and bonding in solid state; main group, transition metal, lanthanide and actinide compounds and reactions; catalysis, spectroscopy, special topics. P/NP or letter grading.

  • 172. Advanced Inorganic Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisite: course 171 with grade of C- or better. Systematic approach to modern inorganic chemistry, structure and bonding of inorganic molecules and solids, structure/reactivity relationships, vibrational spectra of complexes, electronic structure and ligand-field theory, mechanisms of inorganic reactions, bonding and spectroscopy of organometallic compounds, transition metals in catalysis and biology. P/NP or letter grading.

  • C174. Inorganic and Metalorganic Laboratory Methods

    Units: 5

    Lecture, two hours; laboratory, eight hours. Enforced requisites: courses 30CL and 171, with grades of C- or better. Synthesis of inorganic compounds, including air-sensitive materials; Schlenck techniques; chromatographic and ion exchange methods; spectroscopic characterization and literature applications. Concurrently scheduled with course C274. P/NP or letter grading.

  • C175. Inorganic Reaction Mechanisms

    Units: 4

    Lecture, three hours. Requisites: courses 110A, 110B, 113A, and 172, with grades of C- or better. Survey of inorganic reactions; mechanistic principles; electronic structure of metal ions; transition-metal coordination chemistry; inner- and outer-sphere and chelate complexes; substitution, isomerization, and racemization reactions; stereochemistry; oxidation/reduction, free/radical, polymerization, and photochemical reactions of inorganic species. May be concurrently scheduled with course C275. P/NP or letter grading.

  • C176. Group Theory and Applications to Inorganic Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 113A and 172, with grades of C- or better. Group theoretical methods; molecular orbital theory; ligand-field theory; electronic spectroscopy; vibrational spectroscopy. May be concurrently scheduled with course C276A. P/NP or letter grading.

  • C179. Biological Inorganic Chemistry

    Units: 4

    Lecture, three hours. Requisites: courses 153A (or 153AH), 171. Role of metal ions in biology. Topics include interactions of metal ions with proteins, nucleic acids, and other biological molecules; mechanisms of metal ion transport and storage; introduction to metalloenzyme; metalloproteins in electron transfer, respiration, and photosynthesis; metals in medicine. Concurrently scheduled with course C279. P/NP or letter grading.

  • C180. Solid-State Chemistry

    Units: 4

    Lecture, three hours. Requisite: course 172 with grade of C- or better. Survey of new materials and methods for their preparation and characterization, with emphasis on band theory and its relationship to chemical, optical, transport, and magnetic properties, leading to deeper understanding of these materials. Concurrently scheduled with course C280. P/NP or letter grading.

  • C181. Polymer Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 30B, 110A. Synthesis of organic and inorganic macromolecules, thermodynamic and statistical mechanical descriptions of unique properties of polymers, polymer characterization methods, and special topics such as conductive and biomedical polymers and polymeric reagents in synthesis. Concurrently scheduled with course C281. P/NP or letter grading.

  • 184. Chemical Instrumentation

    Units: 5

    Lecture, two hours; laboratory, eight hours. Enforced requisites: courses 30CL and 110A, with grades of C- or better. Theory and practice of instrumental techniques of chemical and structural analysis, including atomic absorption spectroscopy, gas chromatography, mass spectrometry, nuclear magnetic resonance, polarography, X-ray fluorescence, and other modern methods. P/NP or letter grading.

  • 185. Materials Chemistry Laboratory

    Units: 5

    (Formerly numbered C185.) Lecture, two hours; laboratory, eight hours. Requisites: courses 30AL, 110A, 113A, 171. Materials synthesis and physical properties of complex materials. Combines synthetic skills with fundamental physical understanding and characterization in approximately equal proportions to relate materials synthesis to materials function. Letter grading.

  • 188SA. Individual Studies for USIE Facilitators

    Units: 1

    Tutorial, to be arranged. Enforced corequisite: Honors Collegium 101E. Limited to junior/senior USIE facilitators. Individual study in regularly scheduled meetings with faculty mentor to discuss selected USIE seminar topic, conduct preparatory research, and begin preparation of syllabus. Individual contract with faculty mentor required. May not be repeated. Letter grading.

  • 188SB. Individual Studies for USIE Facilitators

    Units: 1

    Tutorial, to be arranged. Enforced requisite: course 188SA. Enforced corequisite: Honors Collegium 101E. Limited to junior/senior USIE facilitators. Individual study in regularly scheduled meetings with faculty mentor to finalize course syllabus. Individual contract with faculty mentor required. May not be repeated. Letter grading.

  • 188SC. Individual Studies for USIE Facilitators

    Units: 2

    Tutorial, to be arranged. Enforced requisite: course 188SB. Limited to junior/senior USIE facilitators. Individual study in regularly scheduled meetings with faculty mentor while facilitating USIE 88S course. Individual contract with faculty mentor required. May not be repeated. Letter grading.

  • 189. Advanced Honors Seminars

    Units: 1

    Seminar, three hours. Limited to 20 students. Designed as adjunct to undergraduate lecture course. Exploration of topics in greater depth through supplemental readings, papers, or other activities and led by lecture course instructor. May be applied toward honors credit for eligible students. Honors content noted on transcript. P/NP or letter grading.

  • 189HC. Honors Contracts

    Units: 1

    Tutorial, three hours. Limited to students in College Honors Program. Designed as adjunct to upper division lecture course. Individual study with lecture course instructor to explore topics in greater depth through supplemental readings, papers, or other activities. May be repeated for maximum of 4 units. Individual honors contract required. Honors content noted on transcript. Letter grading.

  • 192A. Undergraduate Practicum in Chemistry and Biochemistry

    Units: 4

    Lecture, one hour; laboratory, four hours; workshop, two hours. Enforced requisites: courses 14BL and 14CL, or 20L and 30AL, or Science Education 100SL. Intended for students who are planning careers in secondary science chemistry teaching. Complements service learning California Teach science courses that involve teaching field experiences in middle school and high school classrooms. Examination of chemistry issues such as chemical storage and use, waste management, laboratory organization, safety, and techniques. P/NP or letter grading.

  • 192B. Undergraduate Practicum in Chemistry and Biochemistry

    Units: 4

    Lecture, one hour; laboratory, four hours; workshop, two hours. Enforced requisites: courses 14BL and 14CL, or 20L and 30AL, or Science Education 100SL. Intended for students who are planning careers in secondary science chemistry teaching. Complements service learning California Teach science courses that involve teaching field experiences in middle school and high school classrooms. Examination of chemistry issues such as chemical storage and use, waste management, laboratory organization, safety, and techniques. P/NP or letter grading.

  • 192C. Undergraduate Assistant Education Practicum in Chemistry and Biochemistry

    Units: 4

    Seminar, one hour; assigned setting, six hours. Limited to juniors/seniors. Training and supervised practicum for advanced undergraduate students to assist in chemistry and biochemistry lectures. Students assist in preparation of materials and development of innovative programs under guidance of faculty members and teaching assistants. May not be applied toward course requirements for any departmental major. May be repeated for credit with consent of instructor. Individual contract required. Information and contracts may be obtained from department. P/NP grading.

  • 192D. Undergraduate Assistant Education Practicum in Chemistry and Biochemistry

    Units: 2

    Seminar, one hour; assigned setting, five hours. Limited to juniors/seniors. Training and supervised practicum for advanced undergraduate students to assist in chemistry and biochemistry lectures. Students assist in preparation of materials and development of innovative programs under guidance of faculty members and teaching assistants. May not be applied toward course requirements for any departmental major. May be repeated for credit with consent of instructor. Individual contract required. Information and contracts may be obtained from department. P/NP grading.

  • 193A. Journal Club Seminars: UC LEADS and MARC

    Units: 2

    Seminar, three hours. Designed for juniors/seniors in undergraduate research training programs such as UC LEADS and MARC or those who have strong commitment to pursue graduate studies in natural sciences, engineering, or mathematics. Weekly reading and oral presentations of research or research papers selected from current literature. May be repeated for credit. Letter grading.

  • 193B. Journal Club Seminars: Chemistry and Biochemistry

    Units: 2

    Seminar, three hours. Limited to undergraduate students. Discussion of readings selected from current literature in particular field. May be repeated for credit. P/NP grading.

  • 194. Research Group Seminars: Chemistry and Biochemistry

    Units: 1

    Seminar, three hours. Designed for undergraduate students who are part of research group. Advanced study and analysis of current topics in physical, organic, or inorganic chemistry or biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. May be repeated for credit. P/NP grading.

  • 196A. Research Apprenticeship in Chemistry and Biochemistry

    Units: 2 to 4

    Tutorial, three hours per week per unit. Limited to juniors/seniors. Entry-level research apprenticeship for upper division students under guidance of faculty mentor. Consult department for additional information regarding requirements, enrollment petitions, and written proposal deadlines. May be repeated for maximum of 8 units. Individual contract required. P/NP grading.

  • 196B. Research Apprenticeship in Chemistry and Biochemistry

    Units: 2 to 4

    Tutorial, three hours per week per unit. Enforced requisite: course 196A (8 units). Limited to juniors/seniors. Research apprenticeship for upper division students under guidance of faculty mentor. Consult department for additional information regarding requirements, enrollment petitions, and written proposal deadlines. May be taken for maximum of 4 units. Individual contract required. P/NP or letter grading.

  • 199. Directed Research in Chemistry and Biochemistry

    Units: 2 to 4

    Tutorial, three hours per week per unit. Enforced requisite: course 196A (8 units). Limited to juniors/seniors. Supervised individual research under guidance of faculty mentor. Culminating report required. May be repeated for maximum of 12 units. Individual contract required. P/NP or letter grading.

  • C200. Genomics and Computational Biology

    Units: 5

    Lecture, four hours; discussion, one hour. Introduction for biochemistry students of technologies and experimental data of genomics, as well as computational tools for analyzing them. Biochemistry and molecular biology dissected life into its component parts, one gene at time, but lacked integrative mechanisms for putting this information back together to predict what happens in complete organism (e.g., over 80 percent of drug candidates fail in clinical trials). High-throughput technologies such as sequencing, microarrays, mass-spec, and robotics have given biologists incredible new capabilities to analyze complete genomes, expression patterns, functions, and interactions across whole organisms, populations, and species. Use and analysis of such datasets becomes essential daily activity for biomedical scientists. Core principles and methodologies for analyzing genomics data to answer biological and medical questions, with focus on concepts that guide data analysis rather than algorithm details. Concurrently scheduled with course C100. S/U or letter grading.

  • 201. Scientific Proposal Writing

    Units: 2

    Lecture, three hours. Designed for graduate biochemistry and molecular biology students. How to write scientific proposals to be submitted to funding agencies. How to develop curricula vitae, put together grant proposals, and critique proposals. Letter grading.

  • M202. Bioinformatics Interdisciplinary Research Seminar

    Units: 4

    (Same as Bioinformatics M202.) Seminar, two hours; discussion, two hours. Concrete examples of how biological questions about genomics data map to and are solved by methodologies from other disciplines, including statistics, computer science, and mathematics. May be repeated for credit. S/U or letter grading.

  • 203B. Ethics in Chemical Research

    Units: 2

    Seminar, one hour. Discussion of ethics in graduate education, teaching, and chemical research, including issues such as conflicts of interest, plagiarism, intellectual property, sexual harassment, and other topics related to ethical conduct of research. S/U grading.

  • 203C. Research Integrity and Ethics in Genetics Research

    Units: 2

    Lecture, 90 minutes. Data analysis and management, statistical methods, use of commercial reagents, microscopy data analysis, figure preparation, authorship, mentoring, human subjects protection, animal subject protection, and conflict of interest. May be repeated for credit. S/U grading.

  • 203D. Advanced Topics in Responsible Conduct in Cellular and Molecular Biology Research

    Units: 2

    Seminar, two hours. Enforced requisite: course 203A or 203B or 203C. Cellular and molecular biology Ph.D. students continue to learn how to conduct research in field to reliably advance knowledge while maintaining ethical principles. Designed to be taken in fourth or fifth year of Ph.D. work where students would have already been exposed to many challenges of performing and reporting experiments and who are in stage of their careers where they are beginning to think of applying for postdoctoral fellowships and research and teaching positions. Course helps fulfill training requirement in research integrity for NIH training grants and individual NRSA awards. S/U grading.

  • 204. Student Research Seminar

    Units: 2

    Seminar, one hour. Limited to students supported by UCLA program in Cellular and Molecular Biology Predoctoral Training. Research seminar presented by second- and third-year students. S/U grading.

  • CM205A. Introduction to Chemistry of Biology

    Units: 4

    (Same as Pharmacology M205A.) Lecture, three hours; discussion, one hour. Enforced requisite: course 153A with grade of C- or better. Introduction to chemical biology. Topics include computational chemical biology, utility of synthesis in biochemical research, peptidomimetics, designed reagents for cellular imaging, natural product biosynthesis, protein engineering and directed evolution, cell biology of metal ions, imaging metal ions in cells, metal-containing drugs. Concurrently scheduled with course C105. Letter grading.

  • M205B. Issues on Chemistry/Biology Interface

    Units: 2

    (Same as Pharmacology M205B.) Seminar, one hour. Requisite: course CM205A. Selected talks and papers presented by training faculty on solving problems and utilizing tools in chemistry and molecular biology on chemistry/biology interface (CBI). S/U grading.

  • 206. Chemistry of Biology Seminar

    Units: 2

    Seminar, three hours. Limited to students supported by UCLA program in Chemistry/Biology Interface Predoctoral Training. Current research topics at interface of chemistry and biology. May be repeated for credit. S/U grading.

  • C207. Organometallic Chemistry

    Units: 4

    (Formerly numbered 207.) Lecture/discussion, three hours. Requisite or corequisite: course 172. Survey of synthesis, structure, and reactivity (emphasizing mechanistic approach) of compounds containing carbon bonded to elements selected from main group metals, metalloids, and transition metals, including olefin complexes and metal carbonyls; applications in catalysis and organic synthesis. Concurrently scheduled with course C107. S/U or letter grading.

  • C208. Mass Spectrometry for Chemists and Biochemists

    Units: 2

    Lecture, one hour; laboratory, four hours. Requisite: course 153A. Introduction to principles and practice of organic and inorganic mass spectrometry. Topics include EI, CI, ICPMS, GC/MS, LC/MS, ESI, MALDI, MS/MS protein identification, and proteomics. Concurrently scheduled with course C108. S/U or letter grading.

  • 209. Introduction to Chemistry Research

    Units: 2

    Seminar, two hours. Half-hour presentations each session by three different chemistry professors to introduce their research programs. S/U grading.

  • 210. Advanced Topics in Chemical Research

    Units: 2

    Seminar, one hour. Designed for second-year graduate students to help them engage contemporary challenges in chemical research and their own research projects. Building of critical thinking skills and proposal writing skills. S/U grading.

  • C213B. Physical Chemistry: Molecular Spectroscopy

    Units: 4

    Lecture, three hours; discussion, one hour; tutorial, one hour. Requisite: course 113A. Interaction of radiation with matter, microwave spectroscopy, infrared and Raman spectroscopy, vibrations in polyatomic molecules, electronic spectroscopy, magnetic resonance spectroscopy. Concurrently scheduled with course C113B. Independent study project required of graduate students. S/U or letter grading.

  • C215A. Quantum Chemistry: Methods

    Units: 4

    Lecture, four hours; discussion, one hour. Requisites: course 113A, Mathematics 31A, 31B, 32A, 32B, 33A, with grades of C- or better. Recommended: knowledge of differential equations equivalent to Mathematics 134 or 135 or Physics 131 and of analytic mechanics equivalent to Physics 105A. Course C215A or Physics 115B with grade of C- or better is requisite to C215B. Students entering course C215A are normally expected to take course C215B in following term. Designed for chemistry students with serious interest in quantum chemistry. Postulates and systematic development of nonrelativistic quantum mechanics; expansion theorems; wells; oscillators; angular momentum; hydrogen atom; matrix techniques; approximation methods; time dependent problems; atoms; spectroscopy; magnetic resonance; chemical bonding. May be concurrently scheduled with course C115A. S/U or letter grading.

  • C215B. Quantum Chemistry: Methods

    Units: 4

    Lecture, four hours; discussion, one hour. Requisites: course 113A, C215A or Physics 115B, Mathematics 31A, 31B, 32A, 32B, 33A, with grades of C- or better. Recommended: knowledge of differential equations equivalent to Mathematics 134 or 135 or Physics 131 and of analytic mechanics equivalent to Physics 105A. Students entering course C215A are normally expected to take course C215B in following term. Designed for chemistry students with serious interest in quantum chemistry. Postulates and systematic development of nonrelativistic quantum mechanics; expansion theorems; wells; oscillators; angular momentum; hydrogen atom; matrix techniques; approximation methods; time dependent problems; atoms; spectroscopy; magnetic resonance; chemical bonding. May be concurrently scheduled with course C115B. S/U or letter grading.

  • C215C. Advanced Quantum Chemistry: Applications

    Units: 4

    Lecture, three hours; discussion, one hour. Requisite: course C215B. Topics in quantum chemistry selected from molecular structure, collision processes, theory of solids, symmetry and its applications, and theory of electromagnetic radiation. Concurrently scheduled with course C115C. S/U or letter grading.

  • 215D. Molecular Spectra, Diffraction, and Structure

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: course C215B, Physics 131. Selected topics from electronic spectra of atoms and molecules; vibrational, rotational, and Raman spectra; magnetic resonance spectra; X-ray, neutron, and electron diffraction; coherence effects. S/U or letter grading.

  • 218. Physical Chemistry Student Seminar

    Units: 2

    Seminar, two hours. Seminars presented by staff, outside speakers, postdoctoral fellows, and graduate students. May be repeated for credit. S/U grading.

  • 219E. Seminar: Research in Physical Chemistry -- Dynamics of Molecule-Molecule and Molecule-Surface Reactions

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219I. Seminar: Research in Physical Chemistry -- Spectroscopy of Isolated Molecules, Complexes, and Clusters

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219J. Seminar: Research in Physical Chemistry -- Chemistry and Biophysics of Interfaces

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219K. Seminar: Research in Physical Chemistry -- Statistical Mechanics of Disordered Systems

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219L. Seminar: Research in Physical Chemistry -- Modern Methods for Molecular Reactions and Structure

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219Q. Seminar: Research in Physical Chemistry -- Ultrafast Studies of Chemical Reaction Dynamics in Condensed Phase

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219R. Seminar: Research in Physical Chemistry -- Kinetic, Thermodynamic, and Interfacial Effects in Materials

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219S. Seminar: Research in Physical Chemistry -- Nanoscience

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219T. Seminar: Research in Physical Chemistry -- Single-Molecule Spectroscopy in Biology

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219U. Seminar: Research in Physical Chemistry -- Theory and Applications of Magnetic Resonance Spectroscopy and Imaging

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219V. Seminar: Research in Physical Chemistry -- Complex Fluids: Composition, Structure, and Rheology

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219W. Seminar: Research in Physical Chemistry -- Biophysics and Statistical Mechanics of Soft Matter

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219X. Seminar: Research in Physical Chemistry -- Dynamic Processes in Chemically Reacting Flow Systems

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219Y. Seminar: Research in Physical Chemistry -- Theory and Computation for Materials

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 219Z. Seminar: Research in Physical Chemistry -- Single-Cell Physiology

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in physical chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 221A. Advanced Topics in Physical Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Each course encompasses one recognized specialty in physical chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • 221B. Advanced Topics in Physical Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Each course encompasses one recognized specialty in physical chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • 221C. Advanced Topics in Physical Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Each course encompasses one recognized specialty in physical chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • 221D. Advanced Topics in Physical Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Each course encompasses one recognized specialty in physical chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • 221G. Advanced Topics in Physical Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Each course encompasses one recognized specialty in physical chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • C222. Mathematical Methods for Chemistry

    Units: 4

    Lecture, four hours. Enforced requisites: Mathematics 31A, 31B, 32A, 32B. Review of basic mathematics necessary to study physical chemistry at graduate level, with focus on review of vectors, linear algebra, elementary complex analysis, and solution of ordinary and partial differential equations. Development of problem-solving skills through homework based on these mathematical techniques, with examples from physical chemistry. Concurrently scheduled with course C122. S/U or letter grading.

  • C223A. Classical and Statistical Thermodynamics

    Units: 4

    Lecture, four hours; discussion, one hour. Requisite: course 110B or 156. Recommended: course 113A. Presentation of fundamentals of classical thermodynamics. Principles of statistical thermodynamics: probability, ensembles, partition functions, independent molecules, and perfect gas. Applications of classical and statistical thermodynamics selected from diatomic and polyatomic gases, solid and fluid states, phase equilibria, electric and magnetic effects, ortho-para hydrogen, chemical equilibria, reaction rates, imperfect gas, nonelectrolyte and electrolyte solutions, surface phenomena, high polymers, gravitation. May be concurrently scheduled with course C123A. S/U or letter grading.

  • C223B. Classical and Statistical Thermodynamics

    Units: 4

    Lecture, four hours; discussion, one hour. Requisite: course 110B or 156. Recommended: course 113A. Presentation of fundamentals of classical thermodynamics. Principles of statistical thermodynamics: probability, ensembles, partition functions, independent molecules, and perfect gas. Applications of classical and statistical thermodynamics selected from diatomic and polyatomic gases, solid and fluid states, phase equilibria, electric and magnetic effects, ortho-para hydrogen, chemical equilibria, reaction rates, imperfect gas, nonelectrolyte and electrolyte solutions, surface phenomena, high polymers, gravitation. May be concurrently scheduled with course C123B. S/U or letter grading.

  • M223C. Nonequilibrium Statistical Mechanics and Molecular Biophysics

    Units: 4

    (Same as Physics M215D.) Lecture, three hours. Requisites: courses C215B and C223B, or Physics 215A. Fundamentals of nonequilibrium thermodynamics and statistical mechanics applied to molecular biophysics. S/U or letter grading.

  • 225. Chemical Kinetics

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses C215B, C223B. Classical experimental and theoretical approaches to study of rates and mechanisms of chemical reactions. Modern experimental techniques and molecular-level theory of reaction dynamics. Examples of well-studied elementary reactions. S/U or letter grading.

  • C226A. Computational Methods for Chemists

    Units: 4

    Lecture, four hours; laboratory, four hours. Preparation: programming experience in either BASIC, Fortran, C, C++, Java, or Pascal. Requisites: courses 110A, 113A, Mathematics 33A. Theoretical, numerical, and programming tools for constructing new chemical applications, including simple force fields and resulting statistical mechanics for simple molecules, simple ab-initio methods for organic molecules and nanotubes, and classical dynamics and spectroscopy. Concurrently scheduled with course C126A. S/U or letter grading.

  • C226A. Computational Methods for Chemists

    Units: 4

    Lecture, four hours; laboratory, four hours. Preparation: programming experience in either BASIC, Fortran, C, C++, Java, or Pascal. Requisites: courses 110A, 113A, Mathematics 33B. Theoretical, numerical, and programming tools for constructing new chemical applications, including simple force fields and resulting statistical mechanics for simple molecules, simple ab-initio methods for organic molecules and nanotubes, and classical dynamics and spectroscopy. Concurrently scheduled with course C126A. S/U or letter grading.

  • CM227. Synthetic Biology for Biofuels

    Units: 4

    (Same as Chemical Engineering CM227.) Lecture, four hours; discussion, one hour. Requisites: course 153A, Life Sciences 3, 23L. Engineering microorganisms for complex phenotype is common goal of metabolic engineering and synthetic biology. Production of advanced biofuels involves designing and constructing novel metabolic networks in cells. Such efforts require profound understanding of biochemistry, protein structure, and biological regulations and are aided by tools in bioinformatics, systems biology, and molecular biology. Fundamentals of metabolic biochemistry, protein structure and function, and bioinformatics. Use of systems modeling for metabolic networks to design microorganisms for energy applications. Concurrently scheduled with course CM127. S/U or letter grading.

  • 228. Chemical Physics Seminar

    Units: 2

    Seminar, two hours. Seminars presented by staff, outside speakers, postdoctoral fellows, and graduate students. May be repeated for credit. S/U or letter grading.

  • 229. Introduction to Physical Chemistry Research

    Units: 2

    Lecture, 90 minutes. Designed primarily for entering graduate physical chemistry students. S/U grading.

  • M230B. Structural Molecular Biology

    Units: 4

    (Same as Molecular, Cell, and Developmental Biology M230B.) Lecture, three hours; discussion, one hour. Requisites: Mathematics 3C, Physics 6C. Selected topics from principles of biological structure; structures of globular proteins and RNAs; structures of fibrous proteins, nucleic acids, and polysaccharides; harmonic analysis and Fourier transforms; principles of electron, neutron, and X-ray diffraction; optical and computer filtering; three-dimensional reconstruction. S/U or letter grading.

  • M230D. Structural Molecular Biology Laboratory

    Units: 2

    (Same as Molecular, Cell, and Developmental Biology M230D.) Laboratory, 10 hours. Corequisite: course M230B. Methods in structural molecular biology, including experiments utilizing single crystal X-ray diffraction, low angle X-ray diffraction, electron diffraction, optical diffraction, optical filtering, three-dimensional reconstruction from electron micrographs, and model building. S/U or letter grading.

  • 235E. Seminar: Research in Organic Chemistry -- Theoretical and Physical Organic Chemistry

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235F. Seminar: Research in Organic Chemistry -- Synthetic Methods and Synthesis of Natural Products

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235G. Seminar: Research in Organic Chemistry -- Organometallic Chemistry and Organic Synthesis

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235I. Seminar: Research in Organic Chemistry -- Fullerene Chemistry and Materials Science

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235K. Seminar: Research in Organic Chemistry -- Organic Chemistry in Organized and Restricted Media

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235N. Seminar: Research in Organic Chemistry -- Target- and Diversity-Oriented Synthesis of Natural Products and Product-Like Molecules

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235O. Seminar: Research in Organic Chemistry -- Polymer Chemistry and Biomaterials

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235P. Seminar: Research in Organic Chemistry -- Reaction Discovery and Total Synthesis of Complex Molecules

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235Q. Seminar: Research in Organic Chemistry -- Synthetic Organic Chemistry Research

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 235R. Seminar: Research in Organic Chemistry -- Fluorous Materials, Synthetic Chemistry, and Supermolecular Assembly

    Units: 2

    Seminar/research group meeting, three hours. Advanced study and analysis of current topics in organic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 236. Spectroscopic Methods of Organic Chemistry

    Units: 4

    Lecture, three hours. Requisite or corequisite: course C243A. Problem solving using proton and carbon 13 nuclear magnetic resonance, infrared spectroscopy, and mass spectrometry; new techniques in NMR, IR, and MS, with emphasis on Fourier transform NMR. S/U or letter grading.

  • C240. Bionanotechnology

    Units: 4

    Lecture, three hours. Requisites: courses 30C, 110A. Basic physical, chemical, and biological principles in bionanotechnology; materials and strategies for top-down and bottom-up fabrication of ordered biologically derived molecules, characterization and detection techniques, and biomimetic materials and applications at nanoscale. Concurrently scheduled with course C140. S/U or letter grading.

  • 241A. Special Topics in Organic Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Requisite or corequisite: course C243A. Each course encompasses one recognized specialty in organic chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • 241B. Special Topics in Organic Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Requisite or corequisite: course C243A. Each course encompasses one recognized specialty in organic chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • 241D. Special Topics in Organic Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Requisite or corequisite: course C243A. Each course encompasses one recognized specialty in organic chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • 241F. Special Topics in Organic Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Requisite or corequisite: course C243A. Each course encompasses one recognized specialty in organic chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • C243A. Structure and Mechanism in Organic Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 30C and 30CL (may be taken concurrently), 110B, and 113A, with grades of C- or better. Mechanisms of organic reactions. Acidity and acid catalysis; linear free energy relationships; isotope effects. Molecular orbital theory; photochemistry; pericyclic reactions. May be concurrently scheduled with course C143A. S/U or letter grading.

  • C243B. Organic Chemistry: Mechanism and Structure

    Units: 4

    Lecture, three hours; discussion, one hour. Requisite: course C243A. Mechanisms of organic reactions; structure and detection of reactive intermediates. May be concurrently scheduled with course C143B. S/U or letter grading.

  • 244A. Organic Synthesis: Methodology and Stereochemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Modern synthetic reactions and transformations involving organic substrates. Special emphasis on regents useful in asymmetric induction and stereoselective synthesis of structurally complex target molecules. S/U or letter grading.

  • 244B. Strategy and Design in Organic Synthesis

    Units: 4

    Lecture, three hours. Requisite or corequisite: course C243A. Theory behind planning of syntheses of complex molecules from simpler ones. Organic reactions and their use in synthetic process. Reasoning and art involved in organic synthesis. S/U or letter grading.

  • C245. Theoretical and Computational Organic Chemistry

    Units: 4

    Lecture, two hours; discussion, one hour; computer laboratory, one hour. Requisites: courses 30C, 113A. Applications of quantum mechanical concepts and methods to understand and predict organic structures and reactivities. Computational modeling methods, including laboratory experience with force-field and quantum mechanical computer calculations. Concurrently scheduled with course C145. S/U or letter grading.

  • 247. Organic Colloquium

    Units: 2

    Seminar, two hours. Seminars in organic chemistry and related areas presented by staff, outside speakers, postdoctoral fellows, and graduate students. May be repeated for credit. S/U or letter grading.

  • 248. Organic Chemistry Student Seminar

    Units: 2

  • 248. Organic Chemistry Student Seminar

    Units: 2

    Seminar, two hours. Seminars presented by staff, outside speakers, postdoctoral fellows, and graduate students. May be repeated for credit. S/U or letter grading.

  • 249A. Methods of Materials Chemistry: Synthesis, Characterization, Physical Properties, Applications, and Devices

    Units: 2

    Seminar, two hours. Designed for first-year graduate students to teach advanced problem-solving skills and critical thinking, with focus on problems and recent literature pertaining to materials chemistry. How materials are synthesized and characterized. Discussion of important physical properties, as well as broad range of applications and behavior in devices. S/U grading.

  • 249B. Methods of Chemical Synthesis:cvdganic/Inorganic/Organometallic

    Units: 2

    Seminar, two hours. Designed for first-year graduate students to teach advanced problem-solving skills and critical thinking, with focus on problems and recent literature pertaining to chemical synthesis of organic, inorganic, and organometallic compounds. S/U grading.

  • 249C. Methods of Physical/Theoretical/Biophysical Chemistry

    Units: 2

    Seminar, two hours. Designed for first-year graduate students to teach advanced problem-solving skills and critical thinking, with focus on problems and recent literature pertaining to physical, theoretical, and biophysical chemistry. S/U grading.

  • C250. Research Integrity in Cellular Biology, Molecular Biology, and Biochemistry Research

    Units: 2 or 4

    (Formerly numbered 203A.) Lecture, two hours; discussion, two hours. Data analysis and management, statistical methods, use of antibody and kit reagents, figure preparation, authorship, mentoring, human subjects protection, animal subject protection, and conflict of interest. May be repeated for credit. S/U or letter grading.

  • M252. Seminar: Advanced Methods in Computational Biology

    Units: 2

    (Same as Bioinformatics M252 and Human Genetics M252.) Seminar, one hour; discussion, one hour. Designed for advanced graduate students. Examination of computational methodology in bioinformatics and computational biology through presentation of current research literature. How to select and apply methods from computational and mathematical disciplines to problems in bioinformatics and computational biology; development of novel methodologies. S/U or letter grading.

  • CM255. Mitochondria in Medicine, Biology, and Chemistry

    Units: 1

    (Same as Biological Chemistry M255.) Seminar, two hours every other week. Open to undergraduate and graduate science majors considering or currently conducting research in areas related to mitochondria. Large number of physiological and pathophysiological processes involve mitochondrial function and dysfunction. Focus on understanding how mitochondria metabolism, form, and function impact health and disease. Physiology and cell biology of healthy and dysfunctional mitochondria critically assessed at subcellular, cellular, tissue, and organismal levels. Topics include in-depth analyses of literature and critical evaluation of experimental design and methods of current research. Concurrently scheduled with course C155. S/U grading.

  • 256A. Seminar: Research in Biochemistry -- Biochemistry of Plasma Proteins

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256B. Seminar: Research in Biochemistry -- Biochemistry of Protein Function

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256D. Seminar: Research in Biochemistry -- Transcriptional Control Mechanisms in Drosophila Embryogenesis

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256F. Seminar: Research in Biochemistry -- Current Topics in Prokaryotic Development

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256G. Seminar: Research in Biochemistry -- Nucleic Acid Structure Determination by NMR

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256H. Seminar: Research in Biochemistry -- Basic Mechanisms of Promoter Activation

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256J. Seminar: Research in Biochemistry -- Contractile Proteins in Muscle Contraction and Cell Motility

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256K. Seminar: Research in Biochemistry -- Biochemistry and Molecular Biology of Chlamydomonas

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256L. Seminar: Research in Biochemistry -- Literature of Structural Biology

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256M. Seminar: Research in Biochemistry -- Mechanism and Regulation of Transcription Termination in Eukaryotic Organisms

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256N. Seminar: Research in Biochemistry -- Advanced Topics in Structural Biology

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256O. Seminar: Research in Biochemistry -- Membrane Biophysics

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256P. Seminar: Research in Biochemistry -- Analysis of Protein Structure

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256Q. Seminar: Research in Biochemistry -- Biochemistry and Function of Ubiquinone in Yeast and Higher Eukaryotes

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256R. Seminar: Research in Biochemistry -- Biomolecular Nuclear Magnetic Resonance Spectroscopy and Protein Structure

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256S. Seminar: Research in Biochemistry -- Proteome Bioinformatics

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256T. Seminar: Research in Biochemistry -- RNA Processing and RNA Genomics

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256U. Seminar: Research in Biochemistry -- Mitochondrial Biogenesis and Link to Disease

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256V. Seminar: Research in Biochemistry -- Proteomics and Mass Spectrometry

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256W. Seminar: Research in Biochemistry -- Cytoskeletal Dynamics during Drosophila Oogenesis

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256X. Seminar: Research in Biochemistry -- Microtubule-Based Structures and Human Diseases

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 256Y. Seminar: Research in Biochemistry -- Research in Genomics: Biochemistry, Synthetic Biology, and Genomics

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in biochemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 257. Physical Chemistry of Biological Macromolecules

    Units: 4

    Lecture, one hour; discussion, one hour; laboratory, four hours. Requisite: course 153A. Theory of hydrodynamic, thermodynamic, and optical techniques used to study structure and function of biological macromolecules. S/U or letter grading.

  • 258. Advanced Topics in Biochemistry and Molecular Biology

    Units: 2

    Lecture, two hours. Critical analysis of experimental design and methods in biochemistry and molecular biology. In-depth analysis of literature in one or more areas of current research. May be repeated for credit. S/U or letter grading.

  • CM259. Mechanisms of Gene Regulation

    Units: 4

    (Formerly numbered C259A.) (Same as Biological Chemistry M259.) Lecture, four hours. Mechanisms that control transcription in bacteria. Repression and activation at promoters. Sigma factors and polymerase binding proteins. Signal transduction pathways in transcription. Control of termination. Concurrently scheduled with course C159. S/U or letter grading.

  • C259A. Mechanisms in Regulation of Transcription I

    Units: 2

    First five weeks. Lecture, four hours. Mechanisms that control transcription in bacteria. Repression and activation at promoters. Sigma factors and polymerase binding proteins. Signal transduction pathways in transcription. Control of termination. Concurrently scheduled with course C159A. S/U or letter grading.

  • CM260A. Introduction to Bioinformatics

    Units: 4

    (Same as Bioinformatics M260A, Computer Science CM221, and Human Genetics M260A.) Lecture, four hours; discussion, two hours. Enforced requisites: Computer Science 32 or Program in Computing 10C with grade of C- or better, and one course from Biostatistics 100A, 110A, Civil Engineering 110, Electrical Engineering 131A, Mathematics 170A, or Statistics 100A. Prior knowledge of biology not required. Designed for engineering students as well as students from biological sciences and medical school. Introduction to bioinformatics and methodologies, with emphasis on concepts and inventing new computational and statistical techniques to analyze biological data. Focus on sequence analysis and alignment algorithms. Concurrently scheduled with course CM160A. S/U or letter grading.

  • CM260B. Algorithms in Bioinformatics and Systems Biology

    Units: 4

    (Same as Bioinformatics M260B and Computer Science CM222.) Lecture, four hours; discussion, two hours. Enforced requisites: Computer Science 32 or Program in Computing 10C with grade of C- or better, and one course from Biostatistics 100A, 110A, Civil Engineering 110, Electrical Engineering 131A, Mathematics 170A, or Statistics 100A. Course CM260A is not requisite to CM260B. Designed for engineering students as well as students from biological sciences and medical school. Development and application of computational approaches to biological questions, with focus on formulating interdisciplinary problems as computational problems and then solving these problems using algorithmic techniques. Computational techniques include those from statistics and computer science. Concurrently scheduled with course CM160B. Letter grading.

  • 260BL. Advanced Bioinformatics Computational Laboratory

    Units: 2

    Laboratory, four hours. Enforced requisite: course CM260A. Corequisite: course CM260B. Development and application of computational approaches to ask and answer biological questions by implementing variety of bioinformatics and systems biology algorithms. Advantages and disadvantages of different algorithmic methods for studying biological questions and preliminary understanding of how to compute statistical significance of results. Development of conceptual understanding of implementation of bioinformatics algorithms and foundation for how to do innovative work in these fields. Experience in observing impact of computational complexity of algorithms in computing solutions. S/U or letter grading.

  • C261A. Plant Biochemistry

    Units: 4

    Lecture, three hours; discussion, two hours. Requisite: course 153C. Introduction to distinctive features of plant biochemistry. Topics include photosynthesis, nitrogen metabolism, plant cell wall metabolism, and secondary metabolism in relation to stress. Concurrently scheduled with course C161A. S/U or letter grading.

  • 262. Biochemistry and Molecular Biology of Protein Translocation Systems

    Units: 3

    Lecture, two hours; discussion, two hours. Requisites: courses 269A through 269D. Protein translocation into nucleus, mitochondrion, peroxisome, chloroplast, endoplasmic reticulum, and protein export in bacteria. Letter grading.

  • C263. Membrane Protein Structure and Function

    Units: 4

    Lecture, four hours. Enforced requisite: course 156. Detailed examination of how various membrane proteins work. Topics include lipid bilayer properties and how they affect membrane protein function and biology; membrane protein biogenesis; principles of transport across membranes; how channels, transporters, and receptors work at atomic level. Emphasis on reading and analyzing original research papers. Concurrently scheduled with course C163. S/U or letter grading.

  • C264. Free Radicals in Biology and Medicine

    Units: 2 to 4

    Lecture, three hours. Enforced requisites: courses 153A and either 153B or 153C, with grades of C- or better. Biochemcial reactivity of dioxygen, its role in mitochondrial metabolism, neurodegenerative diseases, apoptosis, and aging. Discussion of radical reactions, how they are harnessed to achieve enzyme catalysis, and how free radicals contribute to or regulate essential biological processes. These same reactions "run amok" under certain types of stress and can contribute to wide variety of diseases, including neurodegenerative diseases (e.g., Huntington's, Parkinson's, and Alzheimer's diseases), mitochondrial diseases, atherosclerosis, and aging. Concurrently scheduled with course C164. S/U or letter grading.

  • C265. Metabolic Control by Protein Modification

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 153A, 153B, 153C. Biochemical basis of controlling metabolic pathways by posttranslational modification of proteins, including phosphorylation and methylation reactions. Concurrently scheduled with course C165. Letter grading.

  • 266. Proteomics and Protein Mass Spectrometry

    Units: 3

    Lecture, two hours. Essential technologies and concepts practiced in proteomics-based research, including methods for protein separation and display, protein quantitation, and protein identification. Emphasis on fundamentals of protein mass spectrometry. S/U or letter grading.

  • 266. Proteomics and Protein Mass Spectrometry

    Units: 4

  • 267. Nanoscience and Chemistry

    Units: 4

    Lecture, four hours. Enforced requisites: courses 110A, 113A, 171, 172. Designed for advanced undergraduate and graduate students. Why nanoscience is important and interesting and critical role of chemistry in nanoscience. Chemistry and physics of variety of synthetic inorganic nanostructures, including metallic nanostructures (nanocrystals, nanorods, nanowires), semiconductor nanostructures (quantum dots/rods, nanowires, plates), and carbon nanostructures (fullerene, nanotubes, graphene). Discussion of synthetic approaches, structures, and physical properties, as well as potential technological opportunities of each. Letter grading.

  • 268. Biochemistry Research Seminar

    Units: 2

    Seminar, two hours. Seminars presented by staff, outside speakers, postdoctoral fellows, and graduate students on topics of current biochemical research interest. May be repeated for credit. S/U or letter grading.

  • 269A. Protein Structure

    Units: 2

    Lecture, five hours; discussion, two hours. Requisites: courses 153A, 153B, 153C, 156. Three-dimensional structure of proteins. Forces that stabilize structure of soluble and membrane proteins. Kinetics of protein folding and role of chaperones. Prediction of protein structure from sequence. Letter grading.

  • 269B. Biocatalysis and Bioenergetics

    Units: 2

    Lecture, five hours; discussion, two hours. Requisites: courses 153A, 153B, 153C, 156. Mechanisms and regulation of protein-mediated catalysis. Proteomics and metabolomics. Concepts in electron, proton, and energy transfer. Energy transducing membranes in chloroplasts and mitochondria. Letter grading.

  • 269C. Nucleic Acid Structure and Catalysis

    Units: 2

    Lecture, five hours; discussion, two hours. Requisites: courses 153A, 153B, 153C, 156. Three-dimensional structure of DNA and RNA. Sequence-specific recognition of DNA and RNA. RNA-catalyzed processes, including self-splicing and peptide bond formation. Letter grading.

  • 269D. Mechanism and Regulation of Gene Expression

    Units: 2

    Lecture, five hours; discussion, two hours. Requisites: courses 153A, 153B, 153C, 156. Mechanism and regulation of transcription in prokaryotes and eukaryotes. Mechanism and regulation of mRNA processing; mRNA export and degradation. Letter grading.

  • 269E. Biomolecular Structure, Catalysis, and Regulation

    Units: 2

    Lecture, five hours; discussion, two hours. Requisites: courses 153A, 153B, 153C, 156. Protein-protein interactions, proteomics, protein networks, regulatory circuits, cellular dynamics, imaging of cellular processes. Letter grading.

  • C270. Biochemistry and Molecular Biology of Photosynthetic Apparatus

    Units: 2 to 4

    Lecture, two to three hours; discussion, zero to two hours. Requisites: courses 153A and 153B, or Life Sciences 3 and 23L, and course 153L. Recommended: courses 153C, 154, Life Sciences 4. Light harvesting, photochemistry, electron transfer, carbon fixation, carbohydrate metabolism, pigment synthesis in chloroplasts and bacteria. Assembly of photosynthetic membranes and regulation of genes encoding those components. Emphasis on understanding of experimental approaches. Concurrently scheduled with course CM170. S/U or letter grading.

  • 271. Advanced Topics in Inorganic Chemistry

    Units: 2 to 4

    Lecture, two to four hours. Each offering encompasses one recognized specialty in inorganic chemistry, generally taught by faculty members whose research interests embrace that specialty. S/U or letter grading.

  • 272A. Seminar: Research in Inorganic Chemistry -- Chemistry of Materials

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272B. Seminar: Research in Inorganic Chemistry -- Metalorganic, Inorganic Biometalorganic Chemistry

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272C. Seminar: Research in Inorganic Chemistry -- Inorganic Spectroscopy

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272D. Seminar: Research in Inorganic Chemistry -- Bioinorganic Chemistry and Biology of Transition Metals and Oxygen

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272G. Seminar: Research in Inorganic Chemistry -- Issues in Chemical Education

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272I. Seminar: Research in Inorganic Chemistry -- Organometallic Chemistry

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272J. Seminar: Research in Inorganic Chemistry -- Reticular Chemistry

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272K. Seminar: Research in Inorganic Chemistry -- Inorganic Nanostructures: Synthesis, Properties, and Functions

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272L. Seminar: Research in Inorganic Chemistry -- Molecular Materials

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • 272M. Seminar: Research in Inorganic Chemistry -- Methodology for Chemical Synthesis of Complex Molecules

    Units: 2

    Seminar, three hours. Advanced study and analysis of current topics in inorganic chemistry. Discussion of current research and literature in research specialty of faculty member teaching course. S/U grading.

  • C274. Inorganic and Metalorganic Laboratory Methods

    Units: 5

    Lecture, two hours; laboratory, eight hours. Enforced requisites: courses 30CL and 171, with grades of C- or better. Synthesis of inorganic compounds, including air-sensitive materials; Schlenck techniques; chromatographic and ion exchange methods; spectroscopic characterization and literature applications. Concurrently scheduled with course C174. S/U or letter grading.

  • C275. Inorganic Reaction Mechanisms

    Units: 4

    Lecture, three hours. Requisites: courses 110A, 110B, 113A, and 172, with grades of C- or better. Survey of inorganic reactions; mechanistic principles; electronic structure of metal ions; transition-metal coordination chemistry; inner- and outer-sphere and chelate complexes; substitution, isomerization, and racemization reactions; stereochemistry; oxidation/reduction, free/radical, polymerization, and photochemical reactions of inorganic species. May be concurrently scheduled with course C175. S/U or letter grading.

  • C276A. Group Theory and Applications to Inorganic Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 113A and 172, with grades of C- or better. Group theoretical methods; molecular orbital theory; ligand-field theory; electronic spectroscopy; vibrational spectroscopy. May be concurrently scheduled with course C176. S/U or letter grading.

  • 276B. Physical Methods in Inorganic Chemistry

    Units: 4

    Lecture, three hours. Requisite: course C276A. Theory and applications of spectroscopic techniques, including magnetic resonance and vibrational and surface science methods, to inorganic compounds and materials. S/U or letter grading.

  • 277. Crystal Structure Analysis

    Units: 4

    Lecture, three hours. Theory and practice of modern crystallography, with emphasis on practical experience in structure determination. Topics include crystallographic symmetry, scattering theory, data collection, Fourier analysis, heavy atom techniques, direct methods, isomorphous replacement, crystallographic refinement, error analysis, and common pitfalls. S/U or letter grading.

  • 278. Inorganic Chemistry Student Seminar

    Units: 2

    Seminar, two hours. Seminars presented by staff, outside speakers, postdoctoral fellows, and graduate students. May be repeated for credit. S/U or letter grading.

  • C279. Biological Inorganic Chemistry

    Units: 4

    Lecture, three hours. Requisites: courses 153A (or 153AH), 171. Role of metal ions in biology. Topics include interactions of metal ions with proteins, nucleic acids, and other biological molecules; mechanisms of metal ion transport and storage; introduction to metalloenzyme; metalloproteins in electron transfer, respiration, and photosynthesis; metals in medicine. Concurrently scheduled with course C179. S/U or letter grading.

  • C280. Solid-State Chemistry

    Units: 4

    Lecture, three hours. Requisite: course 172 with grade of C- or better. Survey of new materials and methods for their preparation and characterization, with emphasis on band theory and its relationship to chemical, optical, transport, and magnetic properties, leading to deeper understanding of these materials. Concurrently scheduled with course C180. S/U or letter grading.

  • C281. Polymer Chemistry

    Units: 4

    Lecture, three hours; discussion, one hour. Requisites: courses 30B, 110A. Synthesis of organic and inorganic macromolecules, thermodynamic and statistical mechanical descriptions of unique properties of polymers, polymer characterization methods, and special topics such as conductive and biomedical polymers and polymeric reagents in synthesis. Concurrently scheduled with course C181. S/U or letter grading.

  • 282. Introduction to Inorganic Chemistry Research

    Units: 2

    Lecture, 90 minutes. Discussion of current research in inorganic chemistry, designed primarily for entering graduate inorganic chemistry students. S/U grading.

  • 283. Evolution of Devices from Concept to Product

    Units: 2

    Seminar, 90 minutes. Required of students in Materials Creation Training Program. Training in fundamental science and engineering to fabricate electrical, photonic, and microelectromechanical devices. Discussion of intellectual property issues and development of business plan. May be repeated for credit. S/U or letter grading.

  • 284. Materials Creation Training Program Brown-Bag Seminar

    Units: 2

    Seminar, one hour. Required of students in Materials Creation Training Program. Research and literature seminar presented by graduate students conducting research in synthesis and characterization of materials and fabrication of electronic and photonic devices. S/U grading.

  • 285. Materials Chemistry Laboratory

    Units: 5

    (Formerly numbered C285.) Lecture, two hours; laboratory, eight hours. Requisites: courses 30AL, 110A, 113A, 171. Materials synthesis and physical properties of complex materials. Combines synthetic skills with fundamental physical understanding and characterization in approximately equal proportions to relate materials synthesis to materials function. Letter grading.

  • M370A. Integrated Science Instruction Methods

    Units: 4

    (Same as Earth, Planetary, and Space Sciences M370A and Physics M370A.) Lecture, two hours; discussion, one hour; laboratory, one hour. Preparation: one introductory lower division year (including laboratory) each of chemistry, life sciences, and physics and at least two Earth science courses, preferably one with field experience. Classroom management, lesson design, assessment, history of science education. S/U or letter grading.

  • M370B. Integrated Science Instruction Methods

    Units: 4

    (Same as Earth, Planetary, and Space Sciences M370B and Physics M370B.) Lecture, two hours; discussion, one hour; laboratory, one hour. Requisite: course M370A or Earth, Planetary, and Space Sciences M370A or Physics M370A. Application of learning theory to science instruction and classroom management, including use of technology, collaborative learning, laboratory safety, ethical issues, field experiences, and professional development. S/U or letter grading.

  • 375. Teaching Appentice Practicum

    Units: 1 to 4

    Seminar, to be arranged. Preparation: apprentice personnel employment as teaching assistant, associate, or fellow. Teaching apprenticeship under active guidance and supervision of regular faculty member responsible for curriculum and instruction at UCLA. May be repeated for credit. S/U grading.

  • 400. Safety in Chemical and Biochemical Research

    Units: 2

    Lecture, two hours. Survey of safe laboratory practices for experimental research in organic, inorganic, and physical chemistry and biochemistry. Topics include laser safety, cryogenic hazards, high- and low-pressure experimentation, gas and carcinogen handling, chemical spills, fire extinguishing, and chemical disposal. S/U grading.

  • 495. Teaching College Chemistry

    Units: 2

    Seminar, two hours; discussion, two hours; 20 hours training during week prior to Fall Quarter. Course for teaching assistants designed to deal with problems and techniques of teaching college chemistry. S/U grading.

  • 596. Directed Individual Study or Research

    Units: 2 to 16

    Tutorial, to be arranged with faculty member who directs study or research. May be repeated for credit. S/U grading.

  • 597. Preparation for M.S. Comprehensive Examination or Ph.D. Qualifying Examinations

    Units: 2 to 4

    Tutorial, to be arranged. May be taken for maximum of 8 units. S/U grading.

  • 598. Research for and Preparation of M.S. Thesis

    Units: 2 to 16

    Tutorial, to be arranged. Each faculty member supervises research of M.S. students and holds research group meetings, seminars, and discussions with students. May be repeated for credit. S/U or letter grading.

  • 599. Research for and Preparation of Ph.D. Dissertation

    Units: 2 to 16

    Tutorial, to be arranged. Each faculty member supervises research of Ph.D. students and holds research group meetings, seminars, and discussions with students. May be repeated for credit. S/U or letter grading.